The CREiGS Mission
The mission of CREiGS for the proposed renewal application is consistent with the current offering of the course which is to train medical/doctoral students, postdoctoral scholars, residents, and fellows, and faculty from academic institutions across the nation to become methodologically proficient in genome science for clinical research. The overall goal of the proposed renewal of CREiGS is to build upon our current focus on genetic epidemiology, statistical methods, computational tools, and facilitating career development by providing formal specialized training in the analysis of scRNA-seq data. Similar to the current offering, participants of CREiGS will be able to apply the necessary quantitative, logical, and computational skills to successfully collaborate within clinical and translational, multidisciplinary research teams by fulfilling the following Core Objectives:
To develop a solid foundation in genome science, especially as it relates to single cell technologies, necessary to independently carry out small-scale clinical research projects.
To proficiently apply appropriate statistical methods and computational tools to perform data manipulation and rigorous and reproducible preliminary or intermediate analysis of scRNA-seq datafor clinical and translational research.
To accurately interpret the relevant findings from independently conducted scRNA-seq-related clinical research projects in genome science.
To evaluate the integrity of scRNA-seq studies, with respect to how the data was collected and analyzed, and identify the major threats to the internal and external validity of the study findings.
To effectively communicate important findings from scRNA-seq studies independently carried out or in the scientific literature to research collaborators, clinical providers and colleagues, patients, and community stakeholders.
To develop optimal communication strategies for successful, multidisciplinary, clinical research collaboration with statisticians, bioinformaticians, genetic epidemiologists, and other experts in genome science.